The two most common sources of OPCs are white pine bark and grape seed. Grape seeds contain 7 to 15 percent more OPCs than white pine bark and can be more potent. In a review of the benefits of the OPCs found in grape seed extract, one study notes that the antioxidant activity of OPCs is generally credited for their other health benefits. The study notes that these include an antimutagenic effect; that is, they inhibit the mutation of DNA. The authors point out that chronic degenerative diseases are believed to be a result of environmental mutagens (substances that cause mutation). OPCs may be able to counter these mutagens.
OPCs also have “cosmetic” value. They protect collagen and elastin, which are an important part of the makeup of skin. It is the interlacing of collagen and elastin that gives skin its strength, elasticity, and smoothness. When these two substances are damaged and the skin loses elasticity, the result can be wrinkles. OPCs help restore damaged collagen and elastin and protect them against further damage.
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Reference AIM’s Proancynol 2000 data sheet 2005